CBD For Pain & Inflammation

Updated: Nov 23, 2020

CBD does not produce a euphoric "high" or intoxicating effects but it has become increasingly more popular as an alternative remedy to reduce pain and inflammation.

The human body has an endocannabinoid system (ECS) that receives and translates signals from cannabinoids like CBD. The ECS helps to regulate functions such as sleep, appetite, mood, pain, body temperature and other bodily functions.

CBD has been studied in depth over the past few decades, with pre-clinical and some human trials CBD is displaying efficacy in reducing inflammation, a factor of pain and discomfort present in many health conditions and chronic diseases.

How Does CBD Help With Pain & Inflammation?

CBD stimulates your Vanilloid (TRPV1) receptors, which is known to mediate pain perception, inflammation and body temperature. CBD also has the ability to influence the Adenosine A2A receptors, which is another pathway that CBD exerts it anti-inflammatory properties.

Inflammation is the root of many chronic health conditions, it’s also related to autoimmunity diseases such as type 1 diabetes or rheumatoid arthritis. CBD carries powerful anti-inflammatory and immuno-suppressive properties that can potentially provide relief for those with pain, as a result of inflammation.


Cannabinoids for neuropathic pain. 

Cannabidiol provides long lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors.

Vanilloid TRPV1 receptor mediates the anti-hyperalgesia effect of the non-psychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.

Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor.

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